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Leaving aside such individual and often spectacular cases that have been uncovered, the total number of image manipulations in submitted scientific papers remains unknown and can only be estimated, e.g. by online surveys among scientists. According to such a survey by Martinson et al., 0.3% of 3247 scientists admitted to having “cooked” or falsified research data themselves. About 15% said that they had previously engaged in behaviors such as “dropping observations or data points”, and 4.7% admitted to reusing data in two or more publications (Martinson et al. Free Shipping Fast Delivery Buy Jimmy Choo Womens Norway Knit Jimmy Choo Buy Cheap 2018 Factory Sale Free Shipping 2018 New 39kX94c
) (the survey did not explicitly ask about image manipulation). Recently, based on a visual (“by eye”) screening of 20,621 papers in 40 scientific journals, a group of US-researchers estimated the prevalence of the specific case of inappropriate image duplication at 3.8%, with an increasing tendency during the past decade (Bik et al. 2016 ). This is in line with the observation that in biomedical literature, the number of retractions has increased in the last few years, in many cases due to manipulated images (Krueger Limited Edition Sale Online 2018 New For Sale Vince Leather PointedToe Ankle Boots Cheap Sale Original dwYNJLx
). As efficient and systematic screening of image manipulation is not yet available, it can only be assumed that the technical (software) possibilities of image editing may have increased the probability of image manipulation.

Spectacular cases of fraud with broader media attention refuel the debate on how such manipulation could have been avoided and who will be responsible for better quality control in the future. Journal editors have recognized this problem and organized in the “Committee on publication ethics” (COPE, http://publicationethics.org ). However, journals such as the Journal of Cell Biology controlling systematically images are rather regarded as an exception (Couzin Buscemi Buscemi 100mm Alta Sneakers Pick A Best Pay With Paypal Cheap Online Cheap Sale Perfect 8xblz0aQ
). Responsible editors usually point out reviewers’ and editors’ limited possibilities, as did Donald Kennedy, former editor-in-chief at Science: “Peer review cannot detect [fraud] if it is artfully done. (…) And the reported falsifications in the Hwang paper—image manipulation and fake DNA data—are not the sort that reviewers can easily spot” (Couzin JADA Sandals pink The Cheapest Sale Online 2iZjbsX
). Concerning the above-mentioned case of oncologist Jon Sudbø, Richard Horton, editor of The Lancet, claimed: “This is all so similar to the Hwang thing that we have just been through. (…) Peer review is a great system for detecting badly done research, but if you have an investigator determined to fabricate an entire study, it is not possible to pick it up” (Butler 2006 ). Even clearly fabricated papers have a good chance to be accepted, as John Bohannon showed in an experiment with free access journals (Bohannon 2013 ).

These statements seem to still be true today, at least for more sophisticated manipulations that are undetectable by the bare eye, or for manipulations obviously violating established guidelines such as Nature Journal’s guidelines for “Image integrity and standards” (Nature 2016 ). Such guidelines provide some orientation to which degree an image may still be regarded as authentic after electronic corrections to brightness, contrast etc. To our knowledge, there is still a lack of widely spread and standardized screening methods for reviewers or editors to routinely verify the authenticity of a submitted scientific image. In principle, such screening tools would be useful for everybody involved in the process of quality control. However, journal editors, in particular, should have a choice from a variety of different methods because falsifiers, who also have access to any given screening tool on the free market, will eventually learn to mask their manipulations and render them undetectable by this specific screening tool.

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The widespread adoption of DLT will bring enormous cost savings in three areas, advocates say:

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Blockchain's removal of almost all human involvement in processing is particularly beneficial in cross-border trades, which usually take much longer because of time-zone issues and the fact that all parties must confirm payment processing. Blockchain systems can set up smart contracts or payments triggered when certain conditions are met. The blockchain cotton transaction mentioned above, for example, used a smart contract that automatically made partial payments when the cotton shipment reached specific geographic milestones.

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In 2017, after three years of work, Goldman Sachs Group Inc. (NYSE: ) received a patent for the SETLcoin, which would create near instantaneous trade settlement times (see Big Discount Sale Online H Williams PointedToe Platform Loafers Free Shipping Get Authentic Cheapest Sale Release Dates Pz9Vs
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In 2016, four major banks came together to develop the utility settlement coin (USC), a new digital currency whose use (mainly to buy securities ) would be recorded via blockchain. Led by UBS Group AG (NYSE: ), they include Bank of New York Mellon Corporation (NYSE: ), Deutsche Bank AG (NYSE: ) and Banco Santander S.A. (NYSE: ), along with broker ICAP PLC (LON: IAP). In 2017, six more banks joined them: Barclays Bank, Credit Suisse Group AG (Canadian Imperial Bank of Commerce, HSBC Holdings PLC ( Christian Dior Satin PointedToe Mules New Arrival RFCbrPjdJ
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